LIAISON® Varicella Zoster Virus Diagnostic Solution
Despite extensive immunization programs, Varicella Zoster remains a common seasonal disease, which can cause complications in children, pregnant woman or immunocompromised individuals.
The LIAISON® VZV assay panel (IgG, IgM) is a totally automated and complete solution to support clinicians in the differential diagnosis of varicella zoster virus infection and assessment of immune protection.
LIAISON® VZV IgM
LIAISON® VZV IgM is a CLIA assay for the qualitative determination of specific IgM antibodies to varicella-zoster virus (VZV) in human serum or plasma samples.
LIAISON® VZV IgG
LIAISON® VZV IgG is a CLIA assay for the quantitative determination of specific IgG antibodies to varicella-zoster virus (VZV) in human serum or plasma samples.
Background
Varicella (chicken pox) is an acute, highly contagious viral disease with worldwide distribution and seasonal prevalence in winter and spring. It is characterized by generalized vesicular exanthema often accompanied by fever. Following a primary infection, the virus remains latent in the neural ganglia, and upon subsequent reactivation VZV may cause zoster (shingles), a disease mainly affecting elderly and immunocompromised individuals.
Diagnostic evaluation of VZV infection may be considered to check the immune status and/or identify an active infection, when the individual has atypical and/or severe symptoms and the physician wishes to distinguish between VZV infection and other causes.
Diagnostic testing may also be performed prior to organ transplantation or when a child, pregnant woman or immunocompromised individual has been exposed to a patient with chickenpox.
Why use LIAISON® Varicella Zoster Virus Diagnostic Solution
The LIAISON® VZV Diagnostic Solution provides a fully automated tool for the assessment of immune response to the Varicella Zoster virus in both infection and immunization.
The determination of IgG antibodies with the LIAISON® VZV IgG assay supports the clinician in estimating the immune coverage for varicella zoster, standardized to the WHO reference
LIAISON® VZV IgG: Reference to WHO Standard: Calibrated against WHO International Preparation W1044
LIAISON® VZV IgM can alert the clinician to a current varicella zoster infection, without cross-reacitivty to other common viral Infectious Agents
No cross reactions observed with a panel consisting of antibodies to EBV EBNA, EBV VCA, hCMV, rubella, HSV 1/2, Toxoplasma, Borrelia, ANA.
To be used on
Designed for both specialty and routine tests, LIAISON® XL and LIAISON® XS immunoassay analyzers help your laboratory handle multiple patients and tests simultaneously. LIAISON® systems are trustworthy, intuitive and deliver automated continuous operation with minimal user intervention. The result is reduced turnaround time, optimal cost management and unmatched growth potential.
LIAISON® XL
Designed for large laboratories. Fuse the benefits of high throughput and high sensitivity within a powerful and fully automated system that can seamlessly connect to facilitate Total Laboratory Automation.
LIAISON® XS
A fully automated, easy-to-use benchtop analyzer. Maximize productivity with optimal cost management, no daily maintenance, straightforward integration, and the same capabilities as Diasorin’s high-throughput analyzers.
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