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LIAISON® Vitamin D Diagnostic Solution

Vitamin D deficiency can cause rickets in children and osteoporosis in adults, and several other pathologies.

Diasorin sets the standard in vitamin D testing, supporting the lab and assisting clinicians in making individual patient management decisions.


LIAISON® 25 OH Vitamin D TOTAL Assay

Automated CLIA immunoassay for the quantitative determination of TOTAL 25 OH vitamin D assessment status in adults.



Automated CLIA immunoassay for the quantitative determination of 1,25 vitamin D used in the assessment of the bioactive form of vitamin D especially in patient with renal disease in adults.

Indications for use


A quantitative assay for the assessment of vitamin D

Target patient


Use area

Endocrinology, nephrology, gynecology, geriatric medicine, internal medicine

LIAISON® solution for the diagnosis of Vitamin D deficiency - Diasorin


Diasorin is a world leader in vitamin D testing

25OH vitamin D status is an important indicator of health.
The monitoring of vitamin D is helpful in diseases where calcium and phosphorus homeostasis or bone metabolism are altered. This includes rickets, osteomalacia, osteoporosis, patients with bone fragility, chronic kidney diseases, malabsorption disorders, hepatic failure, and patients under granulomatosis diseases treatment.

How it works

The LIAISON® 25 OH Vitamin D TOTAL assay is a fully automated immunoassay for the direct measurement of 25 OH Vitamin D TOTAL levels. 

Vitamin D deficiency testing


Quick and reliable

It allows quick and reliable determination of vitamin D status and effective therapy monitoring. 


Continuous certification

Demonstrates equal recovery of vitamin D2 and D3 metabolites, no C3- epimer cross-reactivity, and good agreement to LC-MS/MS, maintaining continuous certification by the DEQAS and CDC’s Vitamin D Standardization Certification Program (VDSCP).


Fully automated

Now available in 100-test and 200-test kit formats, 25OHD can be consolidated with Diasorin’s complete bone & mineral metabolism menu including our unique fully automated 1,25 dyhydroxyvitamin D and PTH (Gen II and Gen III) assays. 

A novel, fully automated assay format, extraction free immunoassay for the accurate detection of 1,25 dihydroxyvitamin D.

A quantitative assay for the accurate determination of 1,25 dhydroxyvitamin D


Fully automated

It is the first test that completely eliminates an extraction step, providing a fast, easy, fully automated solution with exceptional accuracy and precision.


High quality test

  • Complete recovery of 1,25(OH)2 D2 and D3
  • Good agreement to RIA and LC-MS/MS methods
  • No biotin interference
  • Many LC-MS/MS methods with single-digit CVs
Use of LIAISON® for the detection of Vitamin D 25 OH and 1,25 OH - Diasorin

Why use LIAISON® Vitamin D Diagnostic Solution

LIAISON® 25 OH Vitamin D TOTAL assay

As the first fully automated 25OHD RIA, Diasorin’s vitamin D assay was used to establish health-based reference values worldwide.
Vitamin D deficiency and insufficiency may result in abnormalities of bone structure in children, muscle and bone weakness and increase falls in the elderly. As a consequence, an early diagnosis of the vitamin D level and its strict monitoring may prevent worsening of bone related conditions.

LIAISON XL® 1,25 OH dihydroxyvitamin D assay

The measurement of 1,25 (OH)2 D is rapidly becoming an efficient tool in the research of diseases and conditions that affect the normal metabolism of phosphorus and calcium.
A strict monitoring assists the clinicians in controlling the CKD disease progression. From a technical perspective the LIAISON® solution eliminates operator-dependent pre-analytical dilapidation and extraction steps, saving the lab time and money while improving precision.

To be used on

Designed for both specialty and routine tests, LIAISON® XL and LIAISON® XS immunoassay analyzers help your laboratory handle multiple patients and tests simultaneously. LIAISON® systems are trustworthy, intuitive and deliver automated continuous operation with minimal user intervention. The result is reduced turnaround time, optimal cost management and unmatched growth potential.

Fully Automated LIAISON® XL System - Diasorin


Designed for large laboratories. Fuse the benefits of high throughput and high sensitivity within a powerful and fully automated system that can seamlessly connect to facilitate Total Laboratory Automation. 

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Fully Automated LIAISON® XS System - Diasorin


A fully automated, easy-to-use benchtop analyzer. Maximize productivity with optimal cost management, no daily maintenance, straightforward integration, and the same capabilities as Diasorin’s high-throughput analyzers. 

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More details about our diagnostic solutions

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Login to our repository for instructions for use and user manuals, assay information, protocols and much more.


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