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LIAISON® C. difficile Diagnostic Solution

C. difficile colitis is more frequent in immunocompromised and debilitated subjects, also and especially due to prolonged antibiotic therapies.

Diasorin’s LIAISON® C. difficile Diagnostic Solution is a completed automated solution that easily supports the diagnostic algorithm steps.

LIAISON® XL / LIAISON® XS

LIAISON® C. difficile GDH

Automated CLIA assay for the detection of Clostridium Difficile GDH antigen, glutamate dehydrogenase, in human feces.

LIAISON® XL / LIAISON® XS

LIAISON® C. difficile Toxin A/B

Automated CLIA assay for the qualitative determination of Clostridium Difficile toxins A and B in human feces.

Indications for use

Diagnosis

Diagnosis of C. difficile in all diagnostic algorithm steps

Target patient

Adults and children who have long antibiotic therapies, hospitalized patients

Use area

Gastroenterology and microbiology

Rapid solution for the identification of C. Difficile - Diasorin

Background

An effective solution for rapid identification of healthcare-associated infection (HAI) by C. difficile

C. difficile is a bacterium that can cause nosocomial intestinal infections with symptoms of varying severity. C. difficile infections are more frequent in immunocompromised and debilitated subjects, and are especially due to prolonged antibiotic therapies. 
This bacterium can be found in normal colonic flora of 2-5% of healthy adults and up to 70% of neonates. Approximately 20-40% of patients hospitalized for more than 2 days become colonized with C. difficile.

ACG Clinical Guidelines (USA) define a 2 step algorithm for diagnosing CD, as also recommended by ESCMID Clinical Guidelines (EU).
The Diasorin LIAISON® C. difficile Diagnostic Solution has a CLIA test for each step:
1st step: the detection of GDH as a screening method.
2nd step: the detection of toxins as a confirmatory method. 

How it works

The LIAISON® C. difficile Diagnostic Solution offers one solution with the same CLIA technology for the determination of C. difficile infections using the same stool sample.

Easy handling of stool sample

01

Simplicity of the process

The use of LIAISON® Quantitative Stool Extraction Device reduces the preparation steps of the extracted stool samples and allows the operator to easily handle the stool, thus saving time.

02

One solution with the same CLIA technology

This panel offers one solution with the same CLIA technology for the determination of C. Difficile infections using the same stool sample.

03

High Performance

  • LIAISON® C. difficile GDH kit: PPA: 99.1%, NPA: 98.9%  
  • LIAISON® C. difficile Toxin A/B kit: PPA: 100%, NPA: 95.6%.
Rapid solution for the identification of C. Difficile - Diasorin

Why use LIAISON® C. difficile Diagnostic Solution

LIAISON® C. difficile Diagnostic Solution delivers a full diagnostic algorithm at every step, providing a safe and complete response for easier diagnosis.

To be used on

Designed for both specialty and routine tests, LIAISON® XL and LIAISON® XS immunoassay analyzers help your laboratory handle multiple patients and tests simultaneously. LIAISON® systems are trustworthy, intuitive and deliver automated continuous operation with minimal user intervention. The result is reduced turnaround time, optimal cost management and unmatched growth potential.

Fully Automated LIAISON® XL System - Diasorin

LIAISON® XL

Designed for large laboratories. Fuse the benefits of high throughput and high sensitivity within a powerful and fully automated system that can seamlessly connect to facilitate Total Laboratory Automation. 

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Fully Automated LIAISON® XS System - Diasorin

LIAISON® XS

A fully automated, easy-to-use benchtop analyzer. Maximize productivity with optimal cost management, no daily maintenance, straightforward integration, and the same capabilities as Diasorin’s high-throughput analyzers. 

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More details about our diagnostic solutions

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Login to our repository for instructions for use and user manuals, assay information, protocols and much more.

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