Luminex® 200™ System
Multiplex up to 100 analytes in a single well of a microtiter plate
The Luminex® 200™ System is a fast, robust, flow-based analyzer combining three core xMAP® Technologies: the fluorescently dyed micron-sized polystyrene microspheres acting as both the identifier and the solid surface to build the assay, a flow cytometry-based instrument integrating key xMAP® detection components, and the xPONENT® Software designed for protocol-based data acquisition with robust data regression analysis.
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Flexibility
Speed
Reliability
Why choose Luminex® 200™
A robust and reliable multiplexing system with thousands of citations.
Genomic and proteomics drug discovery
- Single nucleotide polymorphisms (SNPs)
- Expression analysis
- High-throughput compound screening
- Kinase selectivity screening of candidates
- Serological studies
- Multianalyte drug and drug metabolite profiling
- Toxicology & drug metabolism studies
- Drug target validation (receptor-ligand analysis)
Diagnostic applications
- Genetically inherited disease screening (e.g., cystic fibrosis)
- HLA typing for transplantation
- Autoimmune disease profiling
- Molecular pathogen detection
Research assay applications
- Gene expression analysis
- Genotyping
- Protein expression analysis
- Animal-model serum analyte profiling
- Antibody epitope mapping
- Enzyme/substrate research
- Protein-protein interaction analysis
System
Product |
Registration status |
Part number |
|---|---|---|
Luminex® 200™ System with xPONENT® 4.3 |
IVD RUO |
LX200-XPON-IVD LX200-XPON-RUO |
Specifications
Product Details |
|
|---|---|
General |
|
| Physical Dimensions |
Luminex® 200™: 43 cm (17 in.) x 50.5 cm (20 in.) x 24.5 cm (9.5 in.) (W x D x H)
|
| Weight |
Luminex® 200™: 25 kg (60 lbs) |
| Operating Temperature |
15° – 30°C (59° - 86°F) |
| Operating Humidity |
20 – 80%, non-condensing |
| Shipping and Storage Temperature |
0 – 50°C (32° - 122°F) |
| Shipping and Storage Humidity |
20 – 80%, non-condensing |
| Altitude |
Operation up to 2,400 m (7,874 ft.) above mean sea level |
| System Warm-up Time |
30 min |
| System Initialization |
<45 min. (Including laser warm-up and weekly calibration) |
| System Verification |
5 min |
| Heater Operating Range |
Maintains samples using the heater block (35 - 60°C +/- 2°C of set point; 95 – 131°F) |
| Plate Run Time |
96-well in ≤45 min (up to 12,800 tests/hour) |
| Multiplexing Capability |
Up to 100 analytes per sample (80 on MagPlex® microspheres) |
Electronics |
|
| Input Voltage Range |
100 – 120 V~ ±10%, 1.4 Amp, and 200 – 240 V~ ±10%, 0.8 Amp, 47 – 63 Hz |
| Installation Category |
II - As defined in IEC 61010-1:2010 |
| Pollution Degree |
2 - As defined in IEC 61010-1:2010 |
Optics |
|
| Reporter Channel Detection |
A/D resolution 14 bits |
| Reporter Channel Dynamic Range |
≥ 3.5 decades of detection |
| Reporter Laser |
532 nm, nominal output 10 mW – 15 mW maximum 500 mW, frequency-doubled diode; mode of operation, continuous wave (CW) |
| Classification Laser |
635 nm, 9.1 ± 6%, maximum output 25 mW, diode; mode of operation, continuous wave (CW) |
| Reporter Detector |
Photomultiplier tube, detection bandwidth of 565 – 585 nm |
| Classification Detector |
Avalanche photodiodes with temperature compensation |
| Doublet Discrimination Detector |
Avalanche photodiodes with temperature compensation |
Fluidics |
|
| Cuvette |
200 micron square flow channel |
| Sample Injection Rate |
1 μL/second |
| Sample Uptake Volume |
20 – 200 μL |
| Sheath Flow Rate |
5.4 (± 0.3) mL/min |
| Sheath Pressure |
6 – 9 PSI for normal operations |
PC and Monitor Specifications |
|
| Processor |
3.0 GHz Intel Core i5 (or higher) |
| Main Memory |
8 GB RAM |
| Hard Drive |
1 TB Hard drive space (or higher) |
| Ports |
1x USB 3.1 Type-C |
| Operating System |
Microsoft® Windows® 10 Professional 64 bit, version 1709 or greater |
| Screen Resolution |
SXGA 1,280 x 1,024, 32 bit color |
| Screen Size |
48.3 cm (19 in.) |
| Display Settings |
96 DPI Font |
IQ/OQ
Installation Qualification (IQ) and Operational Qualification (OQ) services are performed by our Field Service Engineers and are critical to ensuring that your instrument is properly installed and operating according to specifications. Luminex offers standard IQ/OQ for new instruments, and Yearly OQ to confirm system reliability of any xMAP® instrument in your laboratory
Product |
Part Number |
|---|---|
Luminex® 200™ IQ/OQ with Installation |
VP-LX-XPON-IQOQ |
Luminex® 200™ Yearly OQ |
VP-LX-XPON-OQ |
Download the informational brochure here.
Software
Product |
Description |
Part number |
|---|---|---|
PC with xPONENT® 4.3 Pre-installed |
xPONENT® Software provides the basic functionality required for instrument control, data acquisition, and data reduction. xPONENT® 4.3 is available as pre-installed software on a Luminex-supplied PC. |
XPON-UPGRD-LX |
21 CFR Part 11 |
For laboratories working under the FDA’s 21 CFR Part 11 regulations, xPONENT® offers multilevel user management, full audit trail, electronic records, and electronic signatures. |
XPON-21CFR |
Automation Connectivity Module |
The automation module and device driver enable communication between the reader and a front-end automation platform. |
XPON-AUTO |
LIS Connectivity Module |
This module allows communication with an external Laboratory Information System (LIS) database by allowing the export of patient result data and the import of patient sample information in ASTM format; connection to your LIS system may require the use of middleware. |
XPON-LIS |
Security Module |
The secure xPONENT® package includes all the basic functionality, plus allows an administrator to set up user access levels. |
XPON-SECURITY |
Reagents
Product |
Registration status |
Part number |
|||
|---|---|---|---|---|---|
Luminex® 200™ (xPONENT® ONLY) Calibration Kit (25 uses) |
IVD RUO |
LX200-CAL-K25 LX2R-CAL-K25 |
|||
Luminex® 200™ (xPONENT® ONLY) Performance Verification Kit (25 Uses) |
IVD RUO |
LX200-CON-K25 LX2R-PVER-K25 |
|||
xMAP® Sheath Fluid PLUS |
IVD RUO |
|
40-50035 |
40-50021 |
|
xMAP® Sheath Concentrate PLUS |
IVD RUO |
|
40-50036 |
40-50023 |
(RUO) This product is for Research Use Only. Not for use in diagnostic procedures.
(IVD) For In Vitro Diagnostic Use. Products are region specific and may not be approved in some countries/regions. If using these products for clinical diagnostic applications, ordering the IVD part number will provide reagents with appropriate In Vitro Diagnostic labeling.
Please contact Luminex at support@luminexcorp.com to obtain the appropriate product information for your country of residence.
Accessories & spare parts
Product |
Part number |
|---|---|
6-Month Preventative Maintenance Kit |
CN-0096-01 |
Automated Maintenance Plate |
CN-0206-01 |
Barcode Scanner, USB |
CN-PC03-01 |
Heater Block (XYP) |
CN-0017-01 |
Intake Air Filter |
CN-0027-01 |
Long Sample Probe |
CN-0007-01 |
Rear Air Filter |
CN-0001-01 |
Sample Needle Height Alignment Kit |
CN-0015-01 |
Sheath Filter with Quick Disconnect |
CN-0010-01 |
Syringe Cylinder with Seal |
CN-0013-01 |
Regulatory
All Luminex instruments are marked in compliance with electrical/safety device standards for appropriate regions. For details on approvals and standards compliance please contact Luminex.
IQ/OQ Services
For more information, please click here, contact your Luminex representative, or email orders@luminexcorp.com.